QuestOmics

About

I built QuestOmics around the questions, not the pipelines.

QuestOmics is a human gut microbiome analysis platform. I focused it on the questions researchers actually ask, not the pipelines that answer them, so you can spend your time on the biology instead of the plumbing.

Sandro Valenzuela

BSc in Bioinformatics · PhD in Infant Gut Microbiome, University of Helsinki

Why I built it

Microbiome research moves slowly when most of the work is plumbing.

Stitching together tools, formats, and clusters eats the time that should go into asking biological questions. QuestOmics removes that friction.

Less plumbing, more biology

You describe what you want to learn, and the platform runs the right, reproducible analyses for you. No tool selection, no glue code, no cluster to babysit.

You pick the question

Instead of picking a pipeline and figuring out what it can tell you, you pick a question. “What organisms dominate this community?”, “Are AMR genes present?”, “How does this cohort compare to published studies?” QuestOmics then activates the curated, compatible analyses for it, and leaves the incompatible ones disabled.

What you can analyze

Built for human gut microbiome data.

One system, and everything in it is tuned for the gut. That is the whole point of it.

The analyses

Taxonomic profilingAMR and resistome screeningFunctional pathwaysDifferential abundanceCohort comparisonDiversity

What you can upload

Shotgun metagenomes, short readShotgun metagenomes, long read16S rRNA ampliconsBacterial isolatesContigs or MAGs

The platform recognizes the input type and routes it to the analyses that can accept it.

How I keep it honest

Cited interpretation, reproducible runs, and your data left alone.

Tables are not interpretation, and a result you cannot reproduce is not a result.

Grounded in literature

Every analysis is paired with Gut Assistant, an AI layer built for microbiome science. It reads from a curated library of peer-reviewed papers and cites only what it can point you to.

Reduced Faecalibacterium prausnitzii in your samples is consistent with the depleted butyrate-producer signature reported in inflammatory states [1].

[1]Sokol et al., PNAS 2008

Reproducible by design

Every run is sealed and version-pinned. Software versions are recorded at execution time, and the methods text is written from that record, ready to paste into a Materials & Methods section.

MetaPhlAn4.0.6
Bowtie22.5.1
marker DBmpa_vJun25

Your data stays yours

Your sequencing data and analysis results belong to you and your study. They are never used for external research, never pooled into external datasets, never sold, and never used to train external models. Data is stored on private, secure hardware in the EU.

Who’s behind it

Built and run by one person.

A microbiome scientist who got tired of the plumbing getting in the way of the questions.

Sandro Valenzuela

Sandro ValenzuelaUniversity of Helsinki

BSc in Bioinformatics · PhD in Infant Gut Microbiome, University of Helsinki

QuestOmics is a one-person labor of love right now. If that resonates, I’d love for you to take it for a spin: open a workspace, upload a dataset, and ask your first question. I read every message and I’d genuinely like to hear what you’re working on.

Prefer email? Write to me anytime at svalenzuela@questomics.app.

See my CV

Have a question, a dataset, or just feedback?

Tell me what you’re working on, whether it’s a question, a dataset, or something you’re stuck on.

or copy svalenzuela@questomics.app

I read every message, and I reply.